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Stem cell therapy in Bangkok Thailand for muscle
damage
Stem cell therapy and treatment for muscle damage. Stem cell therapy
for muscle damage has shown great promise to be able to help those
that have suffered from muscle damage due to various factors. There
have been many studies underway that show that stem cell therapy
really helps the body heal faster.
Researchers have discovered that transplanting specially treated
repair stem cells into damaged muscle makes them twice as big and
strong – and also stops them from ageing.
The results have stunned scientists who still have no real clue
as to why the muscles are so miraculously transformed but hope that
discovering the mechanism could provide a treatment for muscle wasting
in the elderly.
"This was a very exciting and unexpected result," said
Professor Bradley Olwin, the lead author at the University of Colorado.
Muscle stem cells are found between muscle fibres and surrounding
connective tissue and are responsible for the repair and maintenance,
said Prof Olwin.
The researchers transplanted between 10 and 50 stem cells from
a donor mice into the host mice. We found that the transplanted
stem cells are permanently altered and reduce the ageing of the
transplanted muscle, maintaining strength and mass," said Prof
Olwin.
"With further research we may one day be able to greatly resist
the loss of muscle mass, size and strength in humans that accompanies
ageing, as well as chronic degenerative diseases like muscular dystrophy."
A paper on the subject was published in the journal Science Translational
Medicine.
In the experiments, stem cells and muscle fibres were removed from
three-month-old mice, briefly cultured and then transplanted into
another three-month-old mice that had temporarily induced leg muscle
injuries produced by barium chloride injections
The transplanted material seemed to kick the stem cells to a high
gear for self-renewal, essentially taking over the production of
muscle cells.
But the team found that when transplanted stem cells and associated
fibres were injected to healthy mouse limb muscles, there was no
discernible evidence for muscle mass growth.
At the onset of the experiments the research team thought the increase
in muscle mass of the transplanted mice with injured legs would
dissipate within a few months.
Instead, the cells underwent a 50 per cent increase in mass and
a 170 per cent increase in size and remained elevated through the
lifetime of the mice – roughly two years, said Prof Olwin.
Two years for a mice corresponds to about 80 years in a human.
"The environment that the stem cells are injected into is
very important, because when it tells the cells there is an injury,
they respond in a unique way," he said.
"We don't yet know why the cells we transplanted are not responding
to the environment around them in the way that the cells that are
already there respond.
"It's fascinating, and something we need to understand."
Stem cell therapy and treatment for muscle damage in Bangkok Thailand
could soon be available.
Stem cell therapy in Bangkok Thailand
for muscle damage
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