|
Stem cell therapy in Bangkok Thailand for heart
disease
Several clinical trials targeting heart disease have shown that
adult stem cells therapy is safe and effective, and is equally efficient
in old as well as recent infarcts. Adult stem cells therapy for
heart disease was commercially available on at least five continents
at the last count (2011).
Possible methods and mechanisms are:
• Generation of heart muscle cells
• Stimulation of growth of new blood vessels that repopulate
the heart tissue
• Secretion of growth factors, rather than actually incorporating
into the heart
• Assistance via some other mechanism
It may be possible to have adult bone marrow cells differentiate
into heart muscle cells.
Giving people with chronic heart failure injections of their own
bone-marrow stem cells appears to improve their heart function and
extend their lives, new research suggests.
The benefits of the stem cell treatment were apparent within three
months and persisted for the five years the patients were followed.
These tests were carried out in Europe, but obviously these same
results could be achieved in Thailand.
This isn't the first time doctors have reported that stem cells
may help improve the health of people with heart failure or other
heart conditions.
But the multiple patient study is one of the biggest tests to date
of stem cell therapy for heart disease -- and the first to show
that the treatment cuts the risk of death in chronic heart
failure according to the study..
The treatment "has almost no risks and is effective when used
on top of other treatments for chronic heart failure," he says.
The findings were reported here at the European Society of Cardiology
Congress.
Stem Cells and Scarred Heart Tissue
One major cause of heart failure occurs when the heart muscle becomes
scarred and loses its ability to pump enough blood throughout the
body, often after a massive heart attack.
"The hope is that by injecting stem cells into the scarred
area, you will bring life back to that area and induce healthy muscle,"
says American Heart Association spokeswoman Mariell Jessup, MD,
medical director of the Penn Heart and Vascular Center at the University
of Pennsylvania.
Stem cells are at an early stage of maturation and therefore have
the potential to become many different types of cells, including
those in the heart muscle.
Treatment With Stem Cells
In the study, bone marrow stem cells were taken from the area at
the top of the patient’s pelvic bone. Then they were processed
in the lab in such a way as to allow them to be injected into the
scarred heart muscle.
Nearly five years after the study started, seven of the 191 patients
who had the stem cell treatment had died vs. 32 of 200 patients
who did not have the treatment -- a substantial difference.
The stem cell treatment improved the heart's ability to pump blood
and restored blood flow to oxygen-starved heart muscle. Patients
were able to exercise more. They also reported improved quality
of life the study says.
No patient experienced side effects, and all patients continued
to receive optimal medical treatment throughout the study.
"There's been ongoing excitement about using stem cells to
treat heart disease for some time and this study certainly adds
to it, but the therapy is not ready for prime time, she says. One
of the reasons: In the study, people knew whether they were getting
the stem cell treatment, she says.
It's not like the traditional randomized, controlled trial where
people don't know whether they are getting the experimental treatment.
That's what we really need the study says.
In summation, stem cell therapy and treatment in Bangkok Thailand
can be an effective method of treating heart disease in patients
that need stem cell treatments for a heart condition.
Stem cell therapy in Bangkok Thailand
for heart disease
|